This is the Otamatone from Maywa Denki, not to be confused with the Otamatone Jumbo or the Otamatone Deluxe:

They were developed in Japan by the Cube Works Company along with Maywa Denki and Novmichi Tosa, who is demonstrating in these videos. Otomatone’s are known to be the “world’s cutest and weirdest musical instrument”. This appears to be true.

via io9.

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